Enzymes have a globular structure- these are suited to metabolic reactions. Globular structures are ball-like and tend to be flexible.
A small area of an enzyme (3-12 amino acids long) will form a depression on the surface of the enzyme due to how the polypeptide chain has been folded- this is the active site. In this area will be R groups which can form bonds with substrates to make the enzyme substrate complex.
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